The Priority Review

Clinical trials Brief

AstraZeneca registers Phase 3 trial of durvalumab and FLOT in Chinese gastric cancer patients

The study, titled MATTERHORN-CN, plans to enroll 140 participants and plans to start on November 30, 2026. It compares neoadjuvant-adjuvant durvalumab plus FLOT chemotherapy to placebo plus FLOT in resectable gastric and gastroesophageal junction cancer.

Primary source

ClinicalTrials.gov registry record, October 16, 2026

A Study of Neoadjuvant-adjuvant Durvalumab and FLOT Chemotherapy Followed by Adjuvant Durvalumab in Chinese Patients With Resectable GC/GEJC.

Read the source: A Study of Neoadjuvant-adjuvant Durvalumab and FLOT Chemotherapy Followed by Adjuvant Durvalumab in Chinese Patients With Resectable GC/GEJC. clinicaltrials.gov

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