The Priority Review

Policy Brief

CMS final rule strengthens supports lasting drug savings

The CMS final rule establishes a permanent framework for negotiating prices of high-cost drugs, with policies taking effect in 2029. By Feb. 1, 2027, CMS will select up to 20 additional negotiation-eligible drugs for the fourth cycle of negotiations.

Primary source

CMS press release, November 5, 2026

CMS Final Rule Strengthens Supports Lasting Drug Savings

Read the source: CMS Final Rule Strengthens Supports Lasting Drug Savings cms.gov

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