The Priority Review

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Clinical trials

6 stories

Stories

  1. Clinical trials

    TETON-2 results posted: inhaled treprostinil and lung function in idiopathic pulmonary fibrosis

    On October 15, 2026, United Therapeutics' registry entry for the Phase 3 TETON-2 trial posted results. It reports a 95.6 mL difference in FVC change at Week 52 against placebo.

  2. Clinical trials

    AERIFY-1 results posted: itepekimab and COPD exacerbations in former smokers

    On October 15, 2026, Sanofi's registry entry for the Phase 3 AERIFY-1 trial posted results. Both itepekimab doses lowered the annualized rate of moderate or severe exacerbations against placebo.

  3. Clinical trials

    Roche posts Phase 3 results for obinutuzumab in childhood nephrotic syndrome

    Hoffmann-La Roche posted results on October 14, 2026 for its INShore trial of obinutuzumab against mycophenolate mofetil. The record lists sustained complete remission at Week 52 in 95.5% of 44 participants on obinutuzumab and 73.2% of 41 on mycophenolate mofetil.

  4. Clinical trials

    Lee's Pharmaceutical posts Phase 3 results for ciprofloxacin-fluocinolone ear drops

    Lee's Pharmaceutical Limited posted results on October 13, 2026 for a Phase 3 trial of ciprofloxacin 0.3% plus fluocinolone acetonide 0.025% otic solution. The record lists clinical cure for 249 of 295 participants on the combination and 213 of 297 on ciprofloxacin alone.

  5. Clinical trials

    Sanofi posts AERIFY-2 itepekimab COPD results: exacerbation rates in former smokers

    Sanofi and Regeneron Pharmaceuticals posted results for the Phase 3 AERIFY-2 trial of itepekimab in moderate-to-severe COPD on October 9, 2026. In former smokers, the annualized exacerbation rate was 0.879 on placebo and 0.770 on itepekimab every 4 weeks.

  6. Clinical trials

    Roche posts IMpower030 results: atezolizumab before surgery in resectable lung cancer

    Hoffmann-La Roche posted results for the Phase 3 IMpower030 trial on October 9, 2026. In the Stage IIB-IIIB wild-type group, median event-free survival was 34.92 months on placebo and 62.78 months on atezolizumab, both plus chemotherapy.